Suzuki-Miyaura coupling of heteroaryl boronic acids and vinyl chlorides.
نویسندگان
چکیده
A protocol for the Suzuki-Miyaura coupling of heteroaryl boronic acids and vinyl chlorides that minimizes protodeboronation is described. A combination of catalytic amounts of Pd(OAc)(2) and SPhos in conjunction with CsF in isopropanol effectively affords a variety of coupled products. Surprisingly, a dramatic temperature dependence in product selectivity was observed.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 2 شماره
صفحات -
تاریخ انتشار 2012